遥感卫星随遇接入互联网星座和在轨智能处理

低轨互联网星座是当前全球研究和发展的热点,互联网星座支持随遇接入遥感卫星和信息在轨直接处理的应用前景备受期待,但由于轨道高度不同会产生双向高动态异构星座的接入互联问题。首先,通过设定低轨卫星互联网星座在不同轨道特性、不同卫星数量情况下的随遇接入仿真场景,重点探讨了时空非连续可视性和多普勒频移问题对遥感卫星接入性能的影响;其次,基于遥感卫星随遇接入互联网星座场景的特点,分析了不同时延性在轨处理任务的流程及其星地功能分配;最后,对当前在轨智能处理算法存在的问题和未来研究重点进行阐述,为未来低轨互联网星座及遥感卫星的发展和联合组网应用提供可靠的理论支撑。     

25%小偏置碰撞策略及测试评估研究

随着汽车事故的增加,且小重叠碰撞事故死亡率居高不下,小偏置碰撞试验逐渐成为焦点。基于IIHS公布的最新车辆碰撞试验结果,统计超过100余款不同类型的25%小偏置碰撞车辆,建立碰撞转角与碰撞区域的数学模型,将25%小偏置碰撞归结为三种不同的碰撞策略,分别是吸能策略、掠过策略和掠过与吸能策略;并进行试验验证,对三种策略的优缺点进行分析。结果表明,小偏置碰撞试验可运用合理的碰撞策略达到法规要求,对25%小偏置碰撞试验具有一定的参考价值。     

基于禁忌搜索的晶体位置谱分割与校准方法

为满足不同规格晶体探测器对分割校准晶体条响应事件位置数据的需求，开发了一种以禁忌搜索算法为核心，结合UDP数据帧、二维高斯模型及光导折射率的位置信息分割校准方法。实验结果表明，本方法在溢出率为5%时，峰谷比可达1218，空间分辨率达17 mm，晶体条响应位置识别准确度高达99%，滤除了引发伪峰的噪声，避免了过分割问题。在面对多种规格晶体阵列的位置谱时，本方法能依照阵列规格将晶体条区域的响应自动校准编号并输出晶体位置查找表，实现响应事件的精确校准。     

铝合金模板全现浇夹心苯板混凝土外墙施工技术

以郑州高新区岳岗安置房建设项目为EPC总承包项目为例,对全现浇夹心苯板混凝土外墙施工技术的应用及施工技术要点展开讨论,通过墙体中间设置拉缝,减少墙体刚度,实现全现浇混凝土外墙,以提高建筑物的耐久性和安全性,减少后期使用风险和维保费用,为今后类似工程的施工提供理论依据和施工经验.     

Nanovaccine-Mediated Cell Selective Delivery of Neoantigens Potentiating Adoptive Dendritic Cell Transfer for Personalized Immunization

Neoantigen vaccines and adoptive dendritic cell (DC) transfer are major clinical approaches to initiate personalized immunity in cancer patients. However, the immunization efficacy is largely limited by the in vivo trajectory including neoantigens’ access to resident DCs and DCs’ access to lymph nodes (LNs). Herein, an innovative strategy is proposed to improve personalized immunization through neoantigen-loaded nanovaccines synergized with adoptive DC transfer. It is found that it enables selective delivery of neoantigens to resident DCs and macrophages by coating cancer cell membranes onto neoantigen-loaded nanoparticles. In addition, the nanovaccines promote the secretion of chemokine C-C motif ligand 2 (CCL2), CCL3, and C-X-C motif ligand 10 from macrophages, thus potentiating the access of transferred DCs to LNs. This immunization strategy enables coordinated delivery of identified neoantigens and autologous tumor lysate-derived undefined antigens, leading to initiation of antitumor T cell immunity in a personalized manner. It significantly inhibits tumor growth in prophylactic and established mouse tumor models. The findings provide a new vision for potentiating adoptive cell transfer by nanovaccines, which may open the door to a transformative possibility for improving personalized immunization.     

平行坐标技术在干式变压器温度场可视化分析中的应用

本文中笔者将平行坐标技术应用于变压器温度场多维可视化分析,以矿用变压器为例,给出了其高、低压绕组纵向温度分布.     

Preparation and antifouling performance of thin inorganic ultrafiltration membrane via assisted sol-gel method with different composition of dual additives

A novel TiO₂ thin film was prepared on the ceramic hollow fiber by the sol-gel method using poly(vinylpyrrolidone) (PVP) and polyvinyl alcohol (PVA) as additives. SEM images verified the formation of TiO₂ layer with various thickness using different composition of titania sols. The effect of the PVP and PVA contents on the TiO₂ sol properties, the separation and the antifouling performance of the ultrafiltration membranes were investigated thoroughly. When the contents of PVP and PVA were 1.0 wt% and 0.8 wt%, respectively, the resultant membrane showed a thickness of 0.55 μm with a pure water flux of 255 L m^?2 h^?1. In addition, the adherent foulant bovine serum albumin was applied to evaluate the antifouling performance. During the three fouling-recovery cycles, the flux recovery ratio and the flux decay ratio maintained about 99% and 30%. The BSA flux and rejection were still 169 L m^?2 h^?1 and 96.9% after the cycles, indicating a superior antifouling property.     

利用纤维床生物反应器发酵生产链霉素

利用纤维床生物反应器(FBB)发酵生产链霉素,对发酵培养基氮源进行了优化,并与传统搅拌发酵进行了比较。结果表明,以可溶性有机氮源大豆蛋白胨作为发酵培养基氮源,并添加一定量蔗糖,可以完全替代黄豆粉,在1 LFBB中发酵96 h时链霉素效价达到5 567 U·mL~(-1)。在整个发酵过程中,所有菌体都被固定在纤维床反应器上,而发酵液保持澄清,这不仅有利于从无菌体的发酵液中进行产物的提取和纯化,也可以重复利用菌体生产次级代谢产物,从而缩短发酵周期,进一步提高链霉素在发酵过程中的体积生产率。